Enigmas of Primary immunodeficiency disorders genetic diagnosis in our region ,
نویسندگان
چکیده
منابع مشابه
Enigmas of primary immunodeficiency and mycobacterial infection in our territory
Introduction Defects of the immune system in Primary immunodeficient diseases (PIDs) predispose individuals to recurrent infections. Complex genetic components for susceptibility to mycobacterial disease have been suggested. Natural human immunity to the mycobacteria group, including Mycobacterium tuberculosis(MTB), Bacille Calmette-Guérin (BCG) or nontuberculous mycobacteria (NTM) relies on th...
متن کاملDistribution of Primary Immunodeficiency Disorders Diagnosed in a Tertiary Referral Center, Tehran, Iran (2006-2013)
Background: Primary immunodeficiency disorders (PID) are a group of hereditary disorders characterized by an increased susceptibility to severe and recurrent infections, autoimmunity, lymphoproliferative disorders, and malignancy. Objective: To evaluate the demographic and clinical data of PID patients diagnosed in a referral pediatric hospital. Method: All PID cases with a confirmed diagnosis,...
متن کاملPrimary Immunodeficiency Disorders
Immunodeficiency is a common thought among both patients and physicians when confronted with what is perceived as an excessive number, duration, or severity of infections. Because of this, the starting point for evaluating patients for suspected immunodeficiency is based on what constitutes ”too many infections.” It generally is agreed that children with normal immune systems may have an averag...
متن کاملPrimary Immunodeficiency Disorders
Selective IgA deficiency (IgAD) is the most common primary genetic immune defect, with high prevalence in Western countries and relatively low prevalence in the East. The laboratory definition of IgAD is based on the measured serum component. However, the important manifestations of deficiency of IgA, the most prevalent of human antibodies, relate to the absence of secretory IgA, which covers a...
متن کامل"the spectrum of primary immunodeficiency disorders in iran "
epidemiological studies have shown wide geographical and racial variation in the prevalence and patterns of immunodeficiency disorders. to determine the frequency of primary immunodeficiencies (pid) in iran, the iranian primary immunodeficiencies registry (ipidr) was organized in 1999. the diagnosis of immunodeficiency in our patients was based on standard criteria. the patient’s data were extr...
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ژورنال
عنوان ژورنال: Journal of Allergy and Clinical Immunology
سال: 2020
ISSN: 0091-6749
DOI: 10.1016/j.jaci.2019.12.497